Shah Rukh Khan and Sharad Kapoor are the leaders of the two rival gangs. Aishwarya Rai is Shah Rukh Khan's twin sister. Shah Rukh is in love with Priya Gill. Chandrachur Singh is Sharad Kapoor's younger brother who studies in a catering college in Bombay. He comes to Goa to visit his brother and plans to go back and start a restaurant there. He sees Aishwarya and falls in love with her. Chandrachur gives up the idea of going back to Bombay and opens a bakery in Goa. When Shah Rukh comes to know about the romance between Aishwarya and Chandrachur, the fight between the gang turns more violent. How the conflict is resolved is the rest of the story.

When India and Pakistan decide to end their hostilities, there is one army person in India who is unhappy, because of his son's death in the Indo-Pak war. He decides to launch terror attacks and bring an end to peace, and for this purpose he shoots and gravelly injures an Indian army officer. After the death of this officer, Raghavan then decides to do away with the army officer's daughter, Sanjana, who is studying in hostel. Raghavan and his men descend on the hostel and hold over 100 students hostage. There is only one student who can save them, and his name is Ram, he claims he is a student, but is here on a mission - a mission that when told will reveal his real identity and two plans which he must carry out simultaneously.

In 2006, the drug trade is booming; trafficking between Asian and Europe is at an all time high. It is at this time that the Malaysian intelligence and Anti-Narcotic department are called upon for assistance by their Indian counterparts. There are rumors that the gang recently moved their operational headquarters. The cartel is headed by the dreaded Singhania, but what many people do not know is that the business is truly managed by his lieutenant, Don. A man who lives life on the edge, Don is constantly expanding the size of his empire while evading arrest or death at the hands of his enemies, both within and outside the law. He is unstoppable in his pursuit of absolute power. His chief pursuer is an Indian police officer, Desilva. He is a man who has sworn to put an end to this nexus of evil and knows that in capturing Don lies the key to unlock this puzzle. And one day he succeeds. Don is captured and Desilva puts his plan into action...

After the passing of his Trinidad-based father, Surajratan Dhanraj, Casanova Tej is asked by the family solicitor, Vakil, to confirm with his father's last will - namely that he should not only marry Punjab-based Samarpreet Kapoor but must remain married to her for a period of 10 years - or else the entire estate will be transferred to an association that ensures the welfare of turtles and crabs. Tej and Vakil accordingly travel to Punjab, meet Samarpreet and her family, and the couple get married. Tej returns to Trinidad, mails a cheque every month, refuses to communicate with her, and continues with his lifestyle as though he was never married. He is friendly with a supermodel, Shimmer Canhai, and through her meets a young woman, Sammar Capore, and instantly falls in love with her. He accepts a bet with Shimmer that he will successfully woo and wed Sammar but is in for disappointment when she prefers the company of a male named Jigar. Tej sets out to ruin Jigar's career.

Originally from India, Tamil-speaking Shekar Subramaniam lives a middle-classed life abroad along with his wife, Sonia, and a school-going son, Prateek. While Sonia is busy writing a book on converting all female-related expletives to male, her husband is employed with Barron Industries, where the owner insists his staff come up with a plan to launch the ultimate video game or else he will change his organization to a restaurant and hire them as waiters. Hoping to create a super-hero, Shekhar instead faces criticism from Prateek - who hopes to instead see a kick-ass villain. This conversation does change Shekhar's thinking and he sets about to create an indestructible villain, calls him Ra.one (pronounced as in Lankeshwar Ravan) and its arch-enemy G.One (Jeevan). Prateek will have to regret passing on this idea on to his father - for soon their lives will be shattered when the shape-shifting Ra.One will find a way to enter the real world...

Based in Budbuda, Uttar Pradesh, Billu Vilas Pardesi barely makes a living as a barber. His wife, Bindiya, looks after the household, and his children, Gunja and Ronak, are on the verge of being expelled from Gyaan Bharti Vidyalay Higher Secondary School due to non-payment of fees. Then everything changes when Bollywood actor Sahir Khan makes an appearance to film a movie in the town. Rumors spread that Billu is Sahir's close friends, and he becomes a celebrity virtually overnight. His shop gets donations and clientèle, and the school decides to educate his children for free. The trouble begins when townsfolk want to meet with Sahir but Billu is unable to contact him.

Arush Mehra lives a fairly wealthy lifestyle in Sydney, Australia along with two room-mates, Tanmay Joglekar, and Ali Hyder. He works for a food chain, while Tanmay entertains children as 'Eddy Teddy', and Ali takes care of their apartment. All three are womanizers and usually end up sleeping with around 30 different women every year. Arush travels to Delhi to attend Arjun's wedding, and this is where he meets with Isha Sahni, who also resides in Australia, he impresses and wins her over, both get intimate, and shortly thereafter Isha catches him sleeping with Devika, and both split up. Arush returns to Sydney and forgets about this incident. Then one day they find a baby right outside their door with a note to take care of her. The trio suspect each other of being the father, then attempt to get rid of the child, but change their mind, look after her, name her Angel, adore her...

Rizwan Khan, a Muslim from the Borivali section of Mumbai, suffers from Asperger's syndrome, a form of high-functioning autism that complicates socialization. The adult Rizwan marries a Hindu single mother, Mandira, in San Francisco. After 9/11, Rizwan is detained by authorities at LAX who mistake his disability for suspicious behavior. Following his arrest, he meets Radha, a therapist who helps him deal with his situation and his affliction. Rizwan then begins a journey to meet US President Obama to clear his name.